About and Upon

About adverb - On all sides or in every direction.

Upon and about are semantically related in on topic. In some cases you can use "Upon" instead the word "About" as an adverb or a preposition, when it comes to topics like of, to.

Upon preposition - In or into contact with.

About and upon are semantically related in position topic. You can use "About" instead the word "Upon" as an adverb or a preposition, if it concerns topics such as on, of, to.