At one's wits' end and At a loss

At a loss and at one's wits' end are semantically related In some cases you can use "At a loss" instead an adjective phrase "At one's wits' end".

At a loss adjective - Filled with bewilderment.

At one's wits' end and at a loss are semantically related in baffled topic. You can use "At one's wits' end" instead an adjective phrase "At a loss".