Breakthrough
Breakthrough noun - An instance of notable progress in the development of knowledge, technology, or skill.
Usage example: Alexander Fleming's discovery of penicillin was one of medicine's great breakthroughs, for penicillin became the first antibiotic to successfully combat bacterial infections in humans
Lapse is an antonym for breakthrough.
Lapse
Lapse noun - A change in status for the worse usually temporarily.
Breakthrough is an antonym for lapse.
How words are described
Cite this Source
Lapse and Breakthrough. (2016). Retrieved 2026, July 22, from https://thesaurus.plus/related/breakthrough/lapse
Breakthrough & Lapse. N.p., 2016. Web. 22 Jul. 2026. <https://thesaurus.plus/related/breakthrough/lapse>.
Lapse or Breakthrough. 2016. Accessed July 22, 2026. https://thesaurus.plus/related/breakthrough/lapse.
Google Ngram Viewer shows how "breakthrough" and "lapse" have occurred on timeline