Breakthrough
Breakthrough noun - An instance of notable progress in the development of knowledge, technology, or skill.
Usage example: Alexander Fleming's discovery of penicillin was one of medicine's great breakthroughs, for penicillin became the first antibiotic to successfully combat bacterial infections in humans
Reduction is an antonym for breakthrough.
Reduction
How words are described
Cite this Source
Reduction and Breakthrough. (2016). Retrieved 2026, July 22, from https://thesaurus.plus/related/breakthrough/reduction
Breakthrough & Reduction. N.p., 2016. Web. 22 Jul. 2026. <https://thesaurus.plus/related/breakthrough/reduction>.
Reduction or Breakthrough. 2016. Accessed July 22, 2026. https://thesaurus.plus/related/breakthrough/reduction.
Google Ngram Viewer shows how "breakthrough" and "reduction" have occurred on timeline