By then
Once
Once adverb - At an earlier or previous time.
Mutual synonyms
Both terms in one sentence
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It is only once he's become "taller and cooler" that she shows interest, but by then, Yamato's already interested in Mei.
Source: Manga / Say I Love You - And equipment for Rufus is available in only one town (Although by then you've already met him, and he offered to join your party more than once), but unless you backtrack immediately after he joins he gets killed by Gideon before you ever get the chance to shop for his equipment.
Source: Interface Spoiler - She does try and do it with him once she finds out that he's Beautiful All Along, but by then her hymen's rebuilt and damn-near impenetrable.
Source: Sleeps with Everyone but You
Cite this Source
Once and By then. (2016). Retrieved 2026, July 29, from https://thesaurus.plus/related/by_then/once
By then & Once. N.p., 2016. Web. 29 Jul. 2026. <https://thesaurus.plus/related/by_then/once>.
Once or By then. 2016. Accessed July 29, 2026. https://thesaurus.plus/related/by_then/once.
Google Ngram Viewer shows how "by then" and "once" have occurred on timeline