Cause
Cause noun - Someone or something responsible for a result.
Issues
Cause is an antonym for issues in topics: children, distribution, result, point in question, edition of publication.
Both words in one sentence
-
While it would certainly cause some earthquakes or unknown geological issues, it wouldn't be the end of the world.
-
She was addicted to cocaine and had issues with depression but she didn't seem to be a lost cause.
Source: Film / Hannah and Her Sisters -
These reactivated RNA strands can cause any number of physical and mental issues including schizophrenia.
Source: Genetic Memory
Cite this Source
Issues and Cause. (2016). Retrieved 2026, August 14, from https://thesaurus.plus/related/cause/issues
Cause & Issues. N.p., 2016. Web. 14 Aug. 2026. <https://thesaurus.plus/related/cause/issues>.
Issues or Cause. 2016. Accessed August 14, 2026. https://thesaurus.plus/related/cause/issues.
Google Ngram Viewer shows how "cause" and "issues" have occurred on timeline