Cause
Cause noun - Someone or something responsible for a result.
Significant and cause are semantically related. In some cases you can use "Significant" instead an adjective "Cause".
Significant
Significant adjective - Clearly conveying a special meaning (as one's mood).
Cause and significant are semantically related. Sometimes you can use "Cause" instead an adjective "Significant".
Both words in one sentence
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It's also pretty much the only way he can cause any significant damage to bosses due to how miserably low his offense is, coupled with the fact it uses the enemy's stats for the attack instead.
Source: Ditto Fighter - Methanol frequently shows up in significant quantities in moonshine, and it can cause severe vision impairment.
Source: Gargle Blaster / Real Life - Not only that, but ramming will cause your ship to take a significant amount of damage as well.
Source: That One Achievement
Cite this Source
Significant and Cause. (2016). Retrieved 2026, July 21, from https://thesaurus.plus/related/cause/significant
Cause & Significant. N.p., 2016. Web. 21 Jul. 2026. <https://thesaurus.plus/related/cause/significant>.
Significant or Cause. 2016. Accessed July 21, 2026. https://thesaurus.plus/related/cause/significant.
Google Ngram Viewer shows how "cause" and "significant" have occurred on timeline