Comatose and Hopped-up

Comatose adjective - Lacking in gaiety, movement, or animation.

Hopped-up and comatose are semantically related In some cases you can replace phrase "Hopped-up" with "Comatose", this terms are similar.

Hopped-up adjective - Being under the influence of a recreational drug.

Comatose and hopped-up are semantically related in on drugs topic. Sometimes you can use "Comatose" instead an adjective phrase "Hopped-up".