Despisable and Low-down

Low-down and despisable are semantically related in despicable topic. In some cases you can use "Low-down" instead an adjective "Despisable".

Low-down adjective - Not following or in accordance with standards of honor and decency.

Despisable and low-down are semantically related in despicable topic. Sometimes you can use "Despisable" instead an adjective phrase "Low-down".