Disadvantaged and Run-down

Disadvantaged adjective - Kept from having the necessities of life or a healthful environment.

Run-down and disadvantaged are semantically related. In some cases you can use "Run-down" instead an adjective "Disadvantaged".

Run-down adjective - Showing signs of advanced wear and tear and neglect.

Disadvantaged and run-down are semantically related. Sometimes you can use "Disadvantaged" instead an adjective phrase "Run-down".