Extreme
Both words in one sentence
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Convection Schmonvection: We see it where extreme cold should be incredibly harmful.
Source: Disney / Frozen - Dexter: Debra Morgan used the logical extreme variant; these were used on one of her boyfriends, to keep him from doing anything harmful to her.
Source: Kinky Cuffs -
Extreme Omnivore: One of the perks of the Innards power from Don't Lose Your Mind is that you can live on anything small enough to swallow, regardless of how harmful it would be to anyone else.
Cite this Source
Harmful and Extreme. (2016). Retrieved 2026, August 07, from https://thesaurus.plus/related/extreme/harmful
Extreme & Harmful. N.p., 2016. Web. 07 Aug. 2026. <https://thesaurus.plus/related/extreme/harmful>.
Harmful or Extreme. 2016. Accessed August 07, 2026. https://thesaurus.plus/related/extreme/harmful.
Google Ngram Viewer shows how "extreme" and "harmful" have occurred on timeline