Handpicked and Least

Handpicked adjective - Singled out from a number or group as more to one's liking.

Least is an antonym for handpicked in excellent topic.

Least adjective - The superlative of `little' that can be used with mass nouns and is usually preceded by `the'; a quantifier meaning smallest in amount or extent or degree.

Handpicked is an antonym for least.