Inside-out and Through and through

Inside-out adjective - With the inside surface on the outside.

Through and through and inside-out are semantically related. In some cases you can use "Through and through" instead an adverb phrase "Inside-out".

Through and through adverb - To a full extent or degree.

Inside-out and through and through are semantically related. Sometimes you can replace phrase "Inside-out" with "Through and through", this phrases are similar.