Interstate
Interstate noun - One of the system of highways linking major cities in the 48 contiguous states of the United States.
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Synonyms for Interstate
Route and interstate are semantically related. In some cases you can use "Route" instead a noun "Interstate".
Route
Route noun - A passage cleared for public vehicular travel.
Usage example: take Route 190 for six miles, then get off
Interstate and route are semantically related. Sometimes you can use "Interstate" instead a noun "Route".
Mutual synonyms
Both words in one sentence
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Interstate 99 is a notorious case, as its route number was written into the law that authorized the route's Interstate designation, as opposed to being assigned by AASHTO, even though it runs west of Interstate 81.
Source: Artistic License Geography - Even with the story taking place 30 years before the creation of the interstate highway system, there had to be a more direct route than that.
Source: Artistic License Geography - Once a waypoint along Route 66, it was bypassed when the interstate was built, and siphoned away all their traffic and customers.
Source: Dying Town
Cite this Source
Route and Interstate. (2016). Retrieved 2026, August 02, from https://thesaurus.plus/related/interstate/route
Interstate & Route. N.p., 2016. Web. 02 Aug. 2026. <https://thesaurus.plus/related/interstate/route>.
Route or Interstate. 2016. Accessed August 02, 2026. https://thesaurus.plus/related/interstate/route.
Google Ngram Viewer shows how "interstate" and "route" have occurred on timeline