Issue
Issue noun - The descendants of a person, animal, or plant.
Usage example: someone who dies without issue might have their estate turned over to the state
Progenitor is an antonym for issue.
Progenitor
Progenitor noun - A person who is several generations earlier in an individual's line of descent.
Usage example: the progenitors of today's Maya once ruled a mighty empire that stretched across much of Central America
Issue is an antonym for progenitor.
How words are described
Both words in one sentence
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He's kind of bipolar on the hate issue there, showing just how confused one's feelings would be to a vampire progenitor who both blessed and cursed them.
Source: Series / Being Human (UK) -
Made even worse with the tie-in My Little Pony: Fiendship Is Magic issue focusing on him, which reveals he's an Animalistic Abomination — a living embodiment of malevolent shadows that was created to disguise itself as a pony to set its progenitor force/race free from under the Crystal Empire.
Source: Vile Villain, Saccharine Show
Cite this Source
Progenitor and Issue. (2016). Retrieved 2026, August 15, from https://thesaurus.plus/related/issue/progenitor
Issue & Progenitor. N.p., 2016. Web. 15 Aug. 2026. <https://thesaurus.plus/related/issue/progenitor>.
Progenitor or Issue. 2016. Accessed August 15, 2026. https://thesaurus.plus/related/issue/progenitor.
Google Ngram Viewer shows how "issue" and "progenitor" have occurred on timeline