Key
Key adjective - Coming before all others in importance.
Usage example: maintains that Sir Isaac Newton remains the key figure in physical science
Significant and key are semantically related. in crucial topic. In some cases you can use "Significant" instead the word "Key" as an adjective or a noun.
Significant
Significant adjective - Having great meaning or lasting effect.
Usage example: made a significant change in the procedure for applying for citizenship
Key and significant are semantically related. Sometimes you can use "Key" instead the word "Significant" as an adjective or a noun.
Mutual synonyms
Both words in one sentence
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However, the lab he sealed up in the basement (and the fact that he gave Volio a key) causes significant problems.
Source: Literature / All Men of Genius -
One of the key selling points of the game is that every level gives you a significant power boost.
Source: Tabletop Game / Legend System -
A more significant example is "Planet of Fire" where a key plot point is that the hazmat suits are mistaken for gods
Source: Hazmat Suit
Cite this Source
Significant and Key. (2016). Retrieved 2026, August 16, from https://thesaurus.plus/related/key/significant
Key & Significant. N.p., 2016. Web. 16 Aug. 2026. <https://thesaurus.plus/related/key/significant>.
Significant or Key. 2016. Accessed August 16, 2026. https://thesaurus.plus/related/key/significant.
Google Ngram Viewer shows how "key" and "significant" have occurred on timeline