Know the score and Up on

Know the score verb - Be well-informed.

Up on and know the score are semantically related in cognizant topic. In some cases you can use "Up on" instead an adjective phrase "Know the score", when it comes to topics like knowledgeable.

Up on adjective - Being up to particular standard or level especially in being up to date in knowledge.

Know the score and up on are semantically related in cognizant topic. Sometimes you can use "Know the score" instead an adjective "Up on", if it concerns topics such as knowledgeable.