Lay off and Let go

Lay off verb - To bring (as an action or operation) to an immediate end.

Let go and lay off are semantically related in relieve of responsibility topic. In some cases you can use "Let go" instead a verb "Lay off".

Let go verb - Release, as from one's grip.

Lay off and let go are semantically related in responsibility topic. You can use "Lay off" instead a verb phrase "Let go", if it concerns topics such as expel, dismiss, dismiss from responsibility.