Out-of-the-way and Out of

Out-of-the-way adjective - Different from the ordinary in a way that causes curiosity or suspicion.

Out of and out-of-the-way are semantically related. In some cases you can use "Out of" instead an adverb phrase "Out-of-the-way".

Out of adverb - Motivated by.

Out-of-the-way and out of are semantically related. Sometimes you can replace phrase "Out-of-the-way" with "Out of", this phrases are similar.