Responsible
Responsible adjective - Being the one who must meet an obligation or suffer the consequences for failing to do so.
Significant and responsible are semantically related in important topic. In some cases you can use "Significant" instead an adjective "Responsible".
Significant
Significant adjective - Clearly conveying a special meaning (as one's mood).
Responsible and significant are semantically related in important topic. Sometimes you can use "Responsible" instead an adjective "Significant".
Mutual synonyms
Both words in one sentence
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Karma Houdini: Darel and Arabanoo get into a fight that inadvertently causes significant damage to the marketplace, but Darel is the only one who is held responsible for this.
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Failure-to-Save Murder: Sio believes that she's responsible for the blowing-up of a significant part of Kaohsiung, due to her failure to shoot the EIO that triggered the explosion.
Source: Manga / Nobunagun - And that Alpha Centauri B's perihelions (in the game) are responsible for significant climate changes that result in Mind Worms attacking your bases even more ferociously than usual?
Source: Naming Your Colony World
Cite this Source
Significant and Responsible. (2016). Retrieved 2026, July 22, from https://thesaurus.plus/related/responsible/significant
Responsible & Significant. N.p., 2016. Web. 22 Jul. 2026. <https://thesaurus.plus/related/responsible/significant>.
Significant or Responsible. 2016. Accessed July 22, 2026. https://thesaurus.plus/related/responsible/significant.
Google Ngram Viewer shows how "responsible" and "significant" have occurred on timeline