Sinister and Up the creek

Sinister adjective - Being or showing a sign of evil or calamity to come.

Up the creek and sinister are semantically related In some cases you can use "Up the creek" instead an adjective "Sinister".

Sinister and up the creek are semantically related in hopeless topic. Sometimes you can use "Sinister" instead an adjective phrase "Up the creek", if it concerns topics such as futile.