To no purpose and To no avail

To no avail and to no purpose are semantically related in hopeless topic. In some cases you can use "To no avail" instead the phrase "To no purpose" as an adjective or an adverb, when it comes to topics like futile.

To no purpose and to no avail are semantically related in hopeless topic. You can use "To no purpose" instead the phrase "To no avail" as an adjective or an adverb, if it concerns topics such as futile, in vain.