Up on and Up

Up on adjective - Being up to particular standard or level especially in being up to date in knowledge.

Up and up on are semantically related. in cognizant topic. In some cases you can use "Up" instead an adjective "Up on", when it comes to topics like familiar, experienced, knowledgeable, ready in body or mind.

Up adjective - Being at a higher level than average.

Up on and up are semantically related. Sometimes you can use "Up on" instead an adjective "Up".