Give up and Keep off

Give up verb - To give (something) over to the control or possession of another usually under duress.

Keep off and give up are semantically related In some cases you can use "Keep off" instead a verb "Give up".

Keep off verb - Refrain from entering or walking onto.

Give up and keep off are semantically related in abstain from topic. Sometimes you can use "Give up" instead a verb "Keep off".