Loco
Loco adjective - Having or showing a very abnormal or sick state of mind.
Usage example: that dog's plumb loco, just running around in circles all day long
Mad
Mad adjective - Having or showing a very abnormal or sick state of mind.
Usage example: the man who thinks he's been turned into a bug is clearly mad
Loco is a synonym for mad in sane topic. You can use "Loco" instead the word "Mad" as an adjective or a noun, if it concerns topics such as mental. slang substitute
Mutual synonyms
Both words in one sentence
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Papa Loco puts the emphasis on "mad," going about in an unstrapped straightjacket and frequently damaging himself and his allies as much as his enemies.
Source: Mad Bomber -
The National Wrestling Alliance has had two mad musicians known as Mariachi Loco, known for rambling on about tings tangibly related to upcoming matches while strumming their guitars.
Source: Mad Artist -
El Lonje Moco (his name is an untranslatable pun involving mucus, stemming from the phrase "el monje loco", or "the mad monk") is a grotesquely deformed and hunchbacked monk who lives in some sort of dreary, old cellar.
Source: Creator / Eugenio Derbez
Cite this Source
Mad and Loco. (2016). Retrieved 2026, July 29, from https://thesaurus.plus/related/loco/mad
Loco & Mad. N.p., 2016. Web. 29 Jul. 2026. <https://thesaurus.plus/related/loco/mad>.
Mad or Loco. 2016. Accessed July 29, 2026. https://thesaurus.plus/related/loco/mad.
Google Ngram Viewer shows how "loco" and "mad" have occurred on timeline